In order to get more insights into the impact of CETP expression on lipoprotein profile during severe endotoxemia, pooled plasmas obtained from WT and CETPTg mice at baseline and two 2 h after LPS injection (15 mg/kg) were passed through a size-exclusion chromatography device and cholesterol, phospholipid, TG, and protein concentrations were determined in individual fractions. Here, CETP is linked to serum lipopolysaccharide activity.