However, in the present study, the proportions of G0/G1 phase in cell lines with lower ARID5B expression were similar to those in cell lines with higher ARID5B expression, suggesting that cell cycle progression was not a direct mediator in the association between ARID5B gene expression level and sensitivity to MTX in BCP-ALL cell lines. Here, ARID5B is linked to acute lymphoblastic leukemia.