And the 23 differentially methylated CpG sites correspond to 9 genes, and then, 8 of these 9 genes were coding genes—ADCY4, CPXM1, DNM3, GNG4, MAST1, mir129-2, PRDM14, and ZNF177—that had significantly higher levels of DNA methylation in breast cancer. This evidence concerns the gene ADCY4 and breast carcinoma.