As depicted in Fig. 2b, LINC01116 was highly expressed in pcDNA3.1-LINC01116 group (vs. pcDNA3.1 group) and lowly expressed in sh-LINC01116 group (vs. sh-NC), while the mRNA level of LINC01116 in pcDNA3.1 and sh-NC groups was not significantly different from that in Blank group, indicating for satisfactory transfection efficiency of LINC01116 overexpression and knockdown in CRC cells. The gene discussed is LINC01116; the disease is colorectal carcinoma.