To summarise, NPs were able to attenuate the AD effect on memory in (a) mice: transgenic mice expressing human APP and Tau, transgenic mice simultaneously expressing plaques and tangles, and normal mice injected with Aβ1-42 into the brain, and in (b) rats: rats with STZ or scopolamine brain lesions, normal rats injected with amyloid β peptides (Aβ1-40, or Aβ1-42) into the brain, and rats feed with AlCl3. This evidence concerns the gene APP and Alzheimer disease.