CAR-transduced iNKT cells were tested for their cytotoxic activity through the CAR-specific targeting of CD38 or BCMA expressed on multiple myeloma (MM) cell line UM9, as shown in Figure 2A. As expected, the UM9 cells were completely eradicated by the iNKT cells expressing the high affinity BCMA-CAR. This evidence concerns the gene TNFRSF17 and plasma cell myeloma.