Many studies have investigated the link between the lncRNAs located on 8q24.21 and the oncogene MYC and the protein it encodes c-Myc, especially lncRNAs PVT1 and PCAT1, which lie in a close proximity to MYC. Co-amplification of PVT1 and MYC is evident in numerous cancers [150]. Here, MYC is linked to cancer.