In a similar manner, in a 6-week ad libitum high animal compared with high plant protein (30% energy) diet in overweight or obese individuals with nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM), no differences in IL-6 or monocyte chemoattractant protein 1 (MCP-1) was observed, while decreases in IL-18 and TNF-α were observed only in the high animal and in the plant protein group, respectively, suggesting that not only the amount, but also the source of protein intake is important in the inflammation process [16]. This evidence concerns the gene IL18 and type 2 diabetes mellitus.