VCAM1 and metabolic syndrome: Curcumin, a flavonoid that is mainly found in turmeric, curry spice, and ginger, has been shown to decrease SOD, malondialdehyde (MDA) and CRP in patients with metabolic syndrome and IL-1β, TNF-α, ICAM-1 and VCAM-1 in mice, through the inhibition of the TLR4 signaling pathway [69,70].