HOXD13 and neoplasm: In addition, sPD-1 levels tended to be higher in patients who had high PD1+ T cell contents in their tumor tissue (>median, Figure 2A), whereas no differences were observed in pretreatment sPD-1 levels between good and poor performance scores (0–2 vs. 3–4), gender, age (<60 years vs. 60–65 years), or molecular subtype.