NLRP3 and Alzheimer disease: A recent study showed that human AD-MSC-derived EVs exerted suppressive effects on NLRP3 inflammatory responses by reducing expression of inflammatory cytokines (IL-1β and IL-18) and of NLRP3 inflammasome subunits (NLRP3, ASC, and caspase 1) in a human corneal epithelial cell line [140].