For instance, Horikawa et al. (2008) found that SNP rs1470579 IGFBP2 was associated with significant type 2 diabetes risk in 1900 Japanese patients, with odds ratio (OR) of 1.18 (Confidence interval (CI): 1.07–1.31) [67]. The gene discussed is IGFBP2; the disease is type 2 diabetes mellitus.