IGFBP2 and type 2 diabetes mellitus: A cross-sectional study, conducted by Lappas and colleagues (2016), found in 98 patients with gestational diabetes mellitus, after adjusting with age and BMI, that serum IGFBP2 was significantly associated with the development of type 2 diabetes [62], indicating that low postpartum IGFBP2 levels are a significant risk factor for the development of type 2 diabetes in women with a previous history of gestational diabetes.