LCN12 and Familial prostate cancer: For instance, HAGHL (Hydroxyacylglutathione Hydrolase Like), LCN12 (Lipocalin 12), DCST2 (DC-STAMP Domain Containing 2), and PRR7 (Proline Rich 7, Synaptic) not only significantly predicts PC recurrence but also remain risk factor status after adjusting for age at diagnosis, WHO prostate cancer grade, margin status, and tumor stage (Table 4).