Zhang and colleagues [30] explored several histogram-derived PWI-metrics and identified 10th percentile AUC (area under the curve, a DCE-metric) (sensitivity/specificity/AUC 0.78/0.80/0.83) and 10th percentile-Ktrans (sensitivity/specificity/AUC 0.78/0.85/0.80) as the best predictors of IDH-status in a cohort including both LGG and GBM. This evidence concerns the gene IDH1 and glioblastoma.