CD8A and neoplasm: The TME cell population (CD8, CD163 and/or CD68) of the “OSNew” surgical biopsies (n = 17) was analyzed in 287 tumor regions (total of 1260.3 mm2), being morphologically classified into osteolytic (OL, 83.6%, 1118.3 mm2) and osteoid matrix rich (OM, 16.2%, 142.0 mm2) regions.