Other genes with functions in regulation of developmental processes included LIMS3, which has a role in neural tissue patterning and differentiation [41]; PRDM9, which is involved in histone modification and hence, in regulating the epigenetic machinery [42]; and CACNA1C, which is associated with Timothy syndrome (TS), a rare neurodevelopmental disorder [43]. This evidence concerns the gene LIMS3 and neurodevelopmental disorder.