Increased autoantibodies to neuronal proteins such as Tau, NFP, MAG, MBP, and GFAP are consistent with the brain imaging study in another cohort of airline crews which showed decreased brain white matter microstructure and cerebral perfusion, which may be potential causes of cognitive impairments and mood deficits reported by the aircrews [63]. The gene discussed is MAG; the disease is Cognitive impairment.