To a lesser extent, mutations in TGFBR1 (TβRI, TGFβ Type I receptor) have been revealed in ovary, breast and pancreatic cancer or T cell lymphoma, as well as related to the growth of skin tumors in the Ferguson-Smith disease, a multiple self-healing squamous epithelioma [15,16,17,18]. Here, TGFBR1 is linked to multiple self-healing squamous epithelioma.