CYP1A2 and Parkinson disease: Three hundred fifty-eight individuals with PD (48% male, mean age ± standard deviation (SD) = 68.07 ± 9.55 years and mean age at onset ± SD = 63.01 ± 10.12 years) and 358 controls (matched for age and sex), were genotyped for the ADORA2A rs5760423 and CYP1A2 rs762551 polymorphisms.