When the repeated measures ANOVAs were performed followed by a posteriori test, LBP levels were significantly decreased between baseline and 12 months of follow-up (p = 0.033, Figure 1A), whereas a significant reduction in chemerin levels was observed between baseline and 2-month levels (Figure 1B, p = 0.029) in pediatric patients with abdominal obesity that followed the lifestyle intervention. The gene discussed is RARRES2; the disease is Abdominal obesity.