INS and cystic fibrosis: No significant differences were found for anthropometric indices, standard biochemical markers, circulating haemostatic markers or ex vivo platelet aggregation markers between the CF/EF and the EF/CF groups at the beginning of the study except that heart rate (pulses/min), fasting serum insulin concentration (pmol/L) and HOMA-IR were higher in the CF/EF group compared to the EF/CF group (Table 1).