No maspin nuclear positivity was proved for other histological subtypes such: the MSS neuroendocrine tumors (NET), neuroendocrine carcinomas (NEC), mixed adenoneuroendocrine carcinomas (MANEC) or primary choriocarcinoma of the gastrointestinal tract [41,42,43]. This evidence concerns the gene SERPINB5 and digestive system mixed adenoneuroendocrine carcinoma.