IL6 and colonic neoplasm: At this point, it is worth mentioning that interleukin 6 (IL-6) activates NF-κB, enabling its binding to DNA [76], because in the study carried out by Zeng et al. [10], an inhibition of proliferation in colon cancer xenografts in C57BL/6 mice as a result of treatment with MSA (3 mg/kg body weight) and a corresponding decrease in TNF-α and IL-6 levels were observed.