Several studies have reported that molecules such as thrombospondin (TSP), vascular endothelial growth factor (VEGF) and epoxyeicosatrienoic acids (EETs) expressed by ECs in the stable microvasculature might influence tumor angiogenesis, which consequently regulates the maintenance of DTCs dormancy or their switch into a proliferative state [110,111,112,113]. Here, VEGFA is linked to neoplasm.