In the quail-derived cell line QT6, (a non-susceptible cell line to SARS-CoV S-mediated infection) transfected with SARS-CoV S protein, Vesicular stomatitis virus G protein and Ebola virus G protein (EBOV GP), DC-SIGN and L-SIGN expression correlated with enhanced EBOV GP mediated infection. Here, PROS1 is linked to infection.