NFKB1 and colitis: In trinitrobenzene sulfonic acid (TNBS)-induced colitis mice, the andrographolide-lipoic acid conjugate (AL-1) administration alleviates inflammation through inhibiting the expression of TNF-α, IL-1β, and IL-6 and down-regulating the expression of p65 and p-IκB, key regulators of NF-κB pathway.