We confirmed the flow cytometry results by Western blot analysis of MDA-MB-231 (surface CD318+) and MCF7 (surface CD318–) breast cancer cells, and also tested the effect of IFN-γ, which induces expression of CD318 on non-neoplastic cells such as synovial fibroblasts (Figure 1B). The gene discussed is IFNG; the disease is breast carcinoma.