In anotherstudy, serum apelin levels were correlated positively withBMI, IR, serum insulin and TG in women with PCOS.Apelin levels were lower in women with PCOS thancontrols (194.1 ± 50.7 pg/ml vs. 292.1 ± 85.6 pg/ml,respectively) (39). The gene discussed is INS; the disease is polycystic ovary syndrome.