Synbiotic supplementation significantly decreased serum fasting glucose (P=0.02), insulin (P=0.001), ho-meostatic model assessment for insulin resistance (IR, P=0.001), weight (P=0.02), body mass index (BMI, P=0.02),waist circumference (WC, P=0.01), hip circumference (HC, P=0.02), and waist-to-height ratio (WHtR, P=0.02) butsignificantly increased high-density lipoprotein (HDL) cholesterol (P=0.02) compared to the placebo. Here, INS is linked to Insulin resistance.