There were no correlations found in pSS group between concentrations of RF-IgA, RF-IgG with patient’s age and laboratory results such as: WBC, C4, C3 complement components, ALAT, AspAT, presence of cryoglobulins, pH and urine specific gravity or results of FS, OSS, and Schirmer’s test. This evidence concerns the gene C4A and peeling skin syndrome.