Unlike Dgcr8td/td mice that suffer from infertility and uterine deformities, Dgcr8ed/ed and Dgcr8md/md mice showed regular oestrous cycles, showed normal architecture, and produced pups, suggesting that the deletion of Dgcr8 in epithelial and mesenchymal cells does not significantly deteriorate fertility (Figure 1). The gene discussed is DGCR8; the disease is Infertility.