Finally, despite the increase in the protective IL-4 and IL-10 titers 30 days after myocardial infarction, the proinflammatory IL-6 titers were unchanged, and related to the infarcted mass, and lower left ventricular ejection fraction, suggesting the need of additional therapy to improve ventricular remodeling and tissue repair, even after a successful coronary reperfusion. Here, IL4 is linked to myocardial infarction.