We identified two datasets that matched our selection criteria; gene-expression changes in (i) young cells compared to spontaneously immortal cells in which ALDH1A1 was upregulated, while PRMT3 was downregulated (referred hereafter as AL1HighPR3Low) and (ii) lung cancer compared to normal lung cells in which both ALDH1A1 and PRMT3 were upregulated (AL1HighPR3High, Fig. 7a). Here, ALDH1A1 is linked to lung carcinoma.