A broad range of differently sized Tandem Duplications (TD; ~14–93 kb) with a peak at 26 kb was observed, which was clearly distinct from the TD sizes previously observed in other cancers (~11 kb in BRCA1-mutated, ~231 kb in CCNE1-activated, and ~1.7 Mb TDs in CDK12-mutated cancer, respectively)12. Here, CCNE1 is linked to cancer.