MKI67 and neoplasm: Moreover, 3-year overall survival of TNBC patients was less desirable in the highly-expressed hsa_circ_0000199 group than in the lowly-expressed hsa_circ_0000199 group (P=0.001) (Figure 1D), and highly-expressed hsa_circ_0000199 (P=0.048), large tumor size (P=0.014) and high Ki-67 proportion (P=0.012) were independent predictors of unfavorable prognosis among the TNBC population (Table 2 and Supplementary Figure 1).