Additionally, PI3K/Akt/mTOR signaling, downstream pathway of hsa_circ_0000199-miR-206/miR-613 axis in TNBC (Figure 4), was reported to stimulate tumor onset and to potentiate metastasis and proliferation of tumor (e.g. TNBC) cells [54]. The gene discussed is AKT1; the disease is neoplasm.