These data indicated that the upregulated mRNA expression levels of HNRNPA0, HNRNPA2B1, HNRNPC, HNRNPD, PCBP1, HNRNPF, PTBP1, HNRNPK, HNRNPL, HNRNPM, SYNCRIP, HNRNPR, and HNRNPU were significantly associated with high cancer stages and lymph node metastases (LNM) with few exceptions. The gene discussed is HNRNPU; the disease is metastatic malignant neoplasm in the lymph nodes.