These data indicated that the upregulated mRNA expression levels of HNRNPA0, HNRNPA2B1, HNRNPC, HNRNPD, PCBP1, HNRNPF, PTBP1, HNRNPK, HNRNPL, HNRNPM, SYNCRIP, HNRNPR, and HNRNPU were significantly associated with high cancer stages and lymph node metastases (LNM) with few exceptions. The gene discussed is HNRNPD; the disease is cancer.