To assess the effect of TRIM29 on CRC in vivo, one pooled sets of HT29 cells were stably infected with negative control (lenti-NC) or shTRIM29 lentiviral vectors (lenti-shTRIM29) and one pooled sets of HCT116 cells were stably infected with negative control (lenti-NC) or pTRIM29 lentiviral vectors (lenti-pTRIM29) were constructed, and TRIM29 expression was examined by Western blotting. This evidence concerns the gene TRIM29 and colorectal carcinoma.