The highest expression of C2orf27A and IGF2R was found at stage 3 (Figure 6E, 6F), and the lowest expression of CFB and PON1 was observed at stages 3 and 4 (Figure 6G, 6H), although the reason for higher expression at stage 3 relative to stage 4 might be the small sample size (there were only 6 patients with stage 4 HCC). This evidence concerns the gene IGF2R and hepatocellular carcinoma.