CD274 and non-small cell lung carcinoma: Recently, a group of researchers suggested that the use of PD-L1-CAR T in non-small cell lung carcinoma (NSCLC), potentially exhibited antitumor cytotoxic activity against PD-L1high and EGFRmut NSCLC and to some extent leads to the recovery of patients with (PD-L1+) NSCLC [95].