Due to the fact that both the TP63 gene and the Bcl-6 gene are located on chromosome 3q27(− 29) and Bcl-6 gene rearrangements are often seen in diffuse large B-cell lymphomas (DLBCL) [85–88], it has been speculated that the close vicinity of TP63 to Bcl-6 may contribute to its potential involvement in DLBCL tumor progression [60]. Here, TP63 is linked to diffuse large B-cell lymphoma.