Furthermore, sepsis-AKI patients had lower DNA levels of mitochondrial genes ND6, and D-loop, whereas DNA levels of ND1, ND4, COX1 and CYTB were not different between control subjects and patients with sepsis-AKI, probably due to the small sample size and thus a type 2 error (Fig. 6). The gene discussed is MT-CO1; the disease is acute kidney injury.