Further analysis demonstrated that the expression of cell cycle-related genes (CDC6, CDC25A, CDK1, ATM, E2F1, and MKI67) were much higher in breast cancer patients of 3 target genes high expression group or MIR3613 deletion group compared with their counterpart, respectively (Fig. 5f, Supplementary Fig. 8). This evidence concerns the gene MKI67 and breast cancer.