We did not find a significant difference in synovial fluid survivin level between newly diagnosed and biologically treated children with JIA (Me = 125.59 (IQR 76.8–187.30) vs Me 56.30 (IQR 44.20–94.20); p = 0.143) what can be associated with a low statistical power of this comparison. The gene discussed is BIRC5; the disease is juvenile idiopathic arthritis.