It downregulated the expression of downstream proteins phosphorylated Akt (p-AKT), phosphorylated mTOR (p-mTOR), NF-κB, and phosphorylation of inhibitor of kappa B (p-IκB), which play a regulatory role in autophagy, apoptosis, and tumor growth [50,51,146]. Here, AKT1 is linked to neoplasm.