Another recent study used a rat model of hypertension involving NOS inhibition with L-NG-nitroarginine methyl ester (L-NAME) to show that blockade of NF-κB attenuates blood pressure and protects against hypertension-induced kidney damage, underscoring the importance of inflammasome priming in hypertension [136]. The gene discussed is NFKB1; the disease is Hypertension.