Additionally, certain drugs that are often used to treat hypertension such as statins [157], hypoglycemic agents [158], and other anti-inflammatory drugs [159], together with specific inhibitors of NLRP3 such as MCC950 [160], have been reported to improve vascular dysfunction by inhibiting the NLRP3 inflammasome signaling cascade. The gene discussed is NLRP3; the disease is hypertensive disorder.