ACP5 and arthritic joint disease: Lin and colleagues continued the evaluation of the terpenoid excavatolide (150) isolated from the Taiwanese gorgonia coral Briareum excavatum, observing that it inhibited LPS-induced osteoclast-like cell formation and tartrate-resistant acid phosphatase (TRAP) expression, in vitro, while also significantly reducing paw oedema and TRAP-positive multinucleated cell formation in two rat models of experimental arthritis [175].