PTGS2 and colitis: Zbakh and colleagues evaluated the anti-inflammatory properties of the meroterpene 11-hydroxy-1′-O-methylamentadione (AMT-E) (127) isolated from the brown alga Cystoseira usneoides in a murine model of experimental colitis, observing that the levels of myeloperoxidase, cytokines and the expression of the pro-inflammatory genes nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were reduced, concluding that AMG-W might be a candidate for “prevention/treatment of inflammatory bowel disease” [163].