UGT1A1 and Gilbert syndrome: For instance, a humanized transgenic UGT1A-SNP mouse model was established almost a decade ago, which harbors the Gilbert Syndrome-associated UGT1A variant haplotype including UGT1A1*28, UGT1A3-66T>C, UGT1A6*2a, and UGT1A7*3 [109].