These transcription factors, signaling pathways mediating IL6 induction have not been tested in the context of viral infections, which depend significantly on the IL6 for survival and progression of infection such as KSHV [254], H1N1 influenza A infection [255], Pneumovirus infection; closely related to a respiratory syncytial virus [256], Hepatitis B Virus [257], and EBV [258]. The gene discussed is IL6; the disease is viral infectious disease.