LRRK2 variants have also been tested in neurodegenerative diseases such as PSP, AD, dementia with Lewy bodies (DLB), MSA, and essential tremor; specific LRRK2 variants have also been linked to inflammatory diseases such as Crohn’s disease and infectious diseases such as leprosy. This evidence concerns the gene LRRK2 and supranuclear palsy, progressive, 1.