LRRK2 and Alzheimer disease: No significant risk of AD for LRRK2 variants p.R1628P, p.G2385R, p.N551K, p.G2019S, and p.I2020T was detected in a meta-analysis including 13 studies [210]; additionally, no association for essential tremor (ET) risk and LRRK2 risk variants (p.L1114L, p.I1122V, p.R1441C, p.Y1699C, p.I2012T, p.G2019S, p.I2020T, and p.G2385R) has been found [211,212,213,214,215].