Using an APP/PS1 mouse model of AD and a dietary supplementation of anthocyanins extracted from Korean black beans, Ali et al. found that the antioxidative effects of anthocyanins can prevent neurodegeneration through the P13K/Akt/Nrf2 pathway, improve memory related pre- and postsynaptic markers and improve cognitive functions, leading researchers to conclude that anthocyanins may be utilized as a dietary supplement in the aging population to prevent neurological disorders associated with aging [82]. The gene discussed is APP; the disease is Alzheimer disease.