TIMP1 and neoplasm: Of forty mediators evaluated, only TIMP1, IL-13, CCL2, and CCL3 were significantly different between the tumour lysates prepared from the two genotypes, where properdin-deficient mice showed reductions in the chemoattractants CCL2, CCL3, the Th2 cytokine IL-13, and the metalloproteinase inhibitor TIMP-1 (Table 1 and Supplementary Figure S2).