A 14-day model of B16F10 melanoma growth using wildtype and C3−/− mice showed that smaller tumour development was associated with greater IL-10 expression in C3−/− CD8+ T cells, which were increased, while the numbers of CD45+ CD11b+ Gr1+ tumour infiltrating leukocytes remained comparable [10]. The gene discussed is PTPRC; the disease is neoplasm.