MiR-150 appears to modulate sialylation of EGFR via the PI3K/Akt pathway in T-cell acute lymphoblastic leukemia [33, 34], and circRNA_000203 was found to promote cardiac fibrosis by suppressing targets of miR-26b-5p, Col1a2 and CTGF [35]. Here, AKT1 is linked to T-cell acute lymphoblastic leukemia.